Pathogen Metagenomic Sequencing
PMseq™ Pathogen Metagenomic Sequencing
Based on metagenomics, PMseq™ detects more than 36,000 types of pathogens, including bacteria, fungi, viruses, and parasites, in a single next-generation sequencing (NGS) test, along with representative drug resistance and virulence genes, without bias. It significantly increases the positive rate of infection diagnosis, helps enable more targeted antibiotic use, and supports precise diagnosis and management of infections.
Recommended Populations
Patients with Complex or Unclear Infections
Infection cases that remain unresolved after conventional testing.
Patients with Severe Infections
Critically ill patients who need rapid detection and broad coverage.
Immunocompromised Patients
Patients with weakened immune systems who are at high risk of complex infections.
Detection Scope
Detects more than 36,000 pathogens and representative resistance and virulence genes in a single test, and supports analysis of human chromosomal copy number variations (CNVs).
Bacteria
Including 226 Mycobacteria and 179 Mycoplasma / Chlamydia / Rickettsia.
Fungi
Comprehensive fungal genome database.
Viruses
Including 11,545 DNA viruses and 5,134 RNA viruses.
Parasites
Broad coverage of parasitic pathogens.
Drug Resistance Genes
Detects 67 types of antibiotic-resistant bacteria, including genes/sites such as CTX-M, KPC, OXA, MecA, NDM, and 23S rRNA.
Virulence Genes
Including rmpA, rmpA2, iutA, hly, ctxA/ctxB, and others.
Sample Types
Why Choose PMseq™ Pathogen Metagenomic Sequencing
High Data Output
High-throughput sequencing technology increases data output, ensuring highly sensitive pathogen detection and strong support for precise diagnosis of complex infections.
Comprehensive Coverage
Detects 36,000 pathogens in a single test, including drug resistance and virulence genes (e.g., Mycobacterium tuberculosis resistance mutations), for full-spectrum pathogen analysis in complex infections.
Precision Processing
Targeted sample pretreatment and an optimized workflow improve test sensitivity, providing accurate and reliable results for clinical decisions.
Clinical-Grade Database
Supported by a clinically standardized database and intelligent algorithms, ensuring precise reports to guide diagnosis and management of complex infections.
Fully Certified
The end-to-end process, from nucleic acid extraction to analysis software, meets clinical certification requirements, ensuring result quality, authority, and credibility.
Reliable Performance
Standardized quality management ensures stable and consistent testing. Years of passing NHC mNGS external quality assessments validate accuracy and reliability.
Testing Service Process
Physician Orders Test
The physician orders the test based on the clinical presentation.
Sample Collection
Clinical samples are collected according to specimen-type guidelines.
Shipment & Analysis
Samples are sent to the laboratory for analysis.
Results to Physician
The report is provided to the treating physician.